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Structure of 18368-59-7
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3-Bromo-4-methylpyridin-2-ol features a bromine substituent at the 3-position and a methyl group at the 4-position on a pyridin-2-ol scaffold. This electron-deficient heterocycle integrates readily into cross-coupling reactions, offering high functional group tolerance and stability under standard conditions. The phenolic hydroxyl enables direct derivatization or metal coordination, facilitating its use in medicinal chemistry and materials synthesis.
3-Bromo-4-methylpyridin-2-ol serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive bromo group and electron-rich pyridine scaffold. The phenolic hydroxyl group provides a handle for derivatization, while the methyl substituent enhances metabolic stability. Bench-stable and compatible with standard purification protocols, it facilitates efficient synthesis of functionalized heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: