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Structure of 1857296-22-0
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5-Formyl-4-methyl-1H-indole-2-carbonitrile features a fused indole core functionalized with formyl, methyl, and nitrile groups at strategic positions. This electronic profile enables direct participation in transition-metal-catalyzed couplings and cycloadditions. The formyl group offers a handle for derivatization via nucleophilic addition or oxime formation, while the electron-deficient carbonitrile enhances reactivity in conjugate addition processes. Bench-stable under standard conditions, it serves as a modular scaffold for bioactive heterocycle synthesis.
5-Formyl-4-methyl-1H-indole-2-carbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted indole scaffolds. The aldehyde and nitrile functionalities facilitate diverse transformations including reductive amination, nucleophilic addition, and condensation reactions. Its bench-stable nature and compatibility with common protecting group strategies make it well-suited for multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P261-P280-P304+P340-P405
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Lot numbers can be found on the outside label of a product: