Boc-Gly-Gly-Phe-Gly-OH

CAS No. 187794-49-6
Cat. No. CS-0039416
Purity≥96%
MDL No.MFCD02259478

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 187794-49-6

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Description

Boc-Gly-Gly-Phe-Gly-OH is a protected tetrapeptide intermediate featuring a C-terminal glycine residue and a Boc group at the N-terminus. This sequence incorporates a phenylalanine side chain flanked by glycine residues, offering a stable, bench-ready scaffold for peptide synthesis. The Boc protection ensures compatibility with standard deprotection protocols in solid-phase and solution-phase workflows.

Application

Boc-Gly-Gly-Phe-Gly-OH serves as a well-defined tetrapeptide building block for the synthesis of bioactive peptide sequences. The Boc group provides stable N-terminal protection, while the glycine residues offer conformational flexibility and compatibility with standard coupling protocols. This intermediate enables efficient solid-phase and solution-phase peptide assembly, particularly in the construction of cyclic or linear scaffolds relevant to protease inhibitor development and peptide-based drug discovery.

General Information

CAS No. 187794-49-6
Cat. No. CS-0039416
Purity ≥96%
MDL No. MFCD02259478
Storage polypeptide, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₀H₂₈N₄O₇
Molecular Weight 436.46
Synonym(s) None
SMILES CC(C)(C)OC(NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O)=O

Computational Chemistry Data

TPSA 162.93
LogP -0.4444
H_Acceptors 6
H_Donors 5
Rotatable_Bonds 10

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Life Science Linker Peptide Linkers

Life Science ADC Related Compound Cleavable Linker

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Key Words

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Boc-Gly-Gly-Phe-Gly-OH

CAS No. 187794-49-6

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