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CS-W001157 4
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(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(((benzyloxy)(hydroxy)phosphoryl)oxy)phenyl)propanoic acid

  • CAS No. 191348-16-0

  • Cat. No. CS-W009599
  • Purity≥97%
  • MDL No.MFCD00797871

*For research and further manufacturing use only, not for direct human use.

(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(((benzyloxy)(hydroxy)phosphoryl)oxy)phenyl)propanoic acid|CS-W009599

Structure of 191348-16-0

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General Information

  • CAS No. 191348-16-0
  • Cat. No. CS-W009599
  • Purity ≥97%
  • MDL No. MFCD00797871
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₁H₂₈NO₈P
  • Molecular Weight 573.53
  • Synonym(s) L-Phosphotyrosine
  • SMILES O=C(O)[C@H](CC1=CC=C(OP(OCC2=CC=CC=C2)(O)=O)C=C1)NC(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O

Description

This fluorenylmethoxycarbonyl-protected amino acid derivative integrates a phosphoester-linked phenolic moiety, enabling selective conjugation in peptide synthesis. The benzyloxycarbonyl group provides orthogonal protection, while the hydroxyphosphoryl functionality offers enhanced solubility and stability under standard bench conditions.

Synthesis

  • Route1
    • null|null
      76101-29-6
    • In-stock
      (((9H-Fluoren-9-yl)methoxy)carbonyl)-D-tyrosine|CS-0101017
      112883-29-1
    • ~%
    • In-stock
      (2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(((benzyloxy)(hydroxy)phosphoryl)oxy)phenyl)propanoic acid|CS-W009599
      191348-16-0

    References

    • Organic Letters, , vol. 14, # 5 p. 1206 - 1209
  • Route2

    References

    • Organic Letters, , vol. 14, # 5 p. 1206 - 1209
  • Route3

    References

    • Journal of the Chemical Society, Chemical Communications, , # 5 p. 338 - 339

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   131.39
  • LogP   5.917
  • H_Acceptors   6
  • H_Donors   3
  • Rotatable_Bonds   11

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