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CS-W001157 4
Total: USD 88.00

4-(1,3-Dioxolan-2-yl)piperidine

  • CAS No. 202062-80-4

  • Cat. No. CS-0480031
  • Purity≥98%
  • MDL No.MFCD16547635
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(1,3-Dioxolan-2-yl)piperidine|CS-0480031

Structure of 202062-80-4

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Description

4-(1,3-Dioxolan-2-yl)piperidine features a stabilized dioxolane ring fused to the piperidine nitrogen, delivering enhanced moisture tolerance and thermal resilience. This protected amine integrates seamlessly into multistep syntheses, enabling efficient access to complex heterocycles under standard conditions. The dioxolane moiety facilitates selective transformations while minimizing side reactivity.

Application

4-(1,3-Dioxolan-2-yl)piperidine serves as a stable, bench-ready synthon for the introduction of piperidine scaffolds bearing a masked aldehyde functionality. The 1,3-dioxolane ring enables selective deprotection under mild acidic conditions, facilitating downstream transformations such as reductive amination or nucleophilic addition. Its functional group tolerance and ease of purification make it a practical building block in medicinal chemistry workflows for constructing bioactive heterocycles and API intermediates.

General Information

  • CAS No. 202062-80-4
  • Cat. No. CS-0480031
  • Purity ≥98%
  • MDL No. MFCD16547635
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES N1CCC(CC1)C2OCCO2

Computational Chemistry Data

  • TPSA   30.49
  • LogP   0.3589
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group :
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362+P364-P403+P233-P405-P501

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