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Structure of 202062-80-4
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4-(1,3-Dioxolan-2-yl)piperidine features a stabilized dioxolane ring fused to the piperidine nitrogen, delivering enhanced moisture tolerance and thermal resilience. This protected amine integrates seamlessly into multistep syntheses, enabling efficient access to complex heterocycles under standard conditions. The dioxolane moiety facilitates selective transformations while minimizing side reactivity.
4-(1,3-Dioxolan-2-yl)piperidine serves as a stable, bench-ready synthon for the introduction of piperidine scaffolds bearing a masked aldehyde functionality. The 1,3-dioxolane ring enables selective deprotection under mild acidic conditions, facilitating downstream transformations such as reductive amination or nucleophilic addition. Its functional group tolerance and ease of purification make it a practical building block in medicinal chemistry workflows for constructing bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: