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CS-W001157 4
Total: USD 88.00

Methyl 2,4-dioxopentanoate

  • CAS No. 20577-61-1

  • Cat. No. CS-W009533
  • Purity≥98%
  • MDL No.MFCD00043638
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 2,4-dioxopentanoate|CS-W009533

Structure of 20577-61-1

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Description

Methyl 2,4-dioxopentanoate is a versatile β-keto ester featuring a reactive enolizable α-position flanked by two carbonyl groups. This structural motif enables facile alkylation and condensation reactions, making it a key building block in the synthesis of substituted pyrones, heterocycles, and complex natural product intermediates under standard conditions.

Application

Methyl 2,4-dioxopentanoate serves as a versatile synthon in organic synthesis, enabling efficient construction of substituted β-keto ester frameworks. Its α,β-unsaturated carbonyl system facilitates Michael additions, aldol condensations, and heterocycle formation under mild conditions. The molecule exhibits good bench stability and compatibility with common functional groups, simplifying purification and integration into multi-step sequences. Functions as a key building block for bioactive heterocycles and natural product derivatives.

General Information

  • CAS No. 20577-61-1
  • Cat. No. CS-W009533
  • Purity ≥98%
  • MDL No. MFCD00043638
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈O₄
  • Molecular Weight 144.13
  • Synonym(s) Methylacetylpyruvate
  • SMILES CC(CC(C(OC)=O)=O)=O

Computational Chemistry Data

  • TPSA   60.44
  • LogP   -0.2924
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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