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Structure of 211943-27-0
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2-Fluoro-3-iodobenzonitrile features a strategically positioned fluorine and iodine substituent on a benzonitrile scaffold, enabling seamless integration into cross-coupling reactions. The electron-withdrawing nitrile group enhances reactivity, while the ortho-fluoro substitution stabilizes the aryl halide for palladium-catalyzed transformations. This compound serves as a key intermediate in the synthesis of functionalized pharmaceuticals and agrochemicals.
2-Fluoro-3-iodobenzonitrile serves as a versatile building block in cross-coupling chemistry, enabling efficient access to substituted biaryls and heterocycles. The ortho-fluoro and iodo groups offer complementary reactivity for sequential functionalization, while the nitrile moiety provides a handle for downstream transformations. Bench-stable and compatible with palladium-catalyzed reactions, it facilitates rapid diversification in medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: