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Structure of 213622-93-6
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This acetylenic carboxylic acid features a para-ethynylphenyl group linked to a methylene spacer, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC). The terminal alkyne integrates readily into bioconjugation workflows and polymer architectures. Stable under standard conditions with predictable reactivity in click chemistry applications.
2-(4-Ethynylphenyl)acetic acid serves as a versatile building block for Sonogashira coupling and click chemistry applications, enabling efficient access to conjugated aryl-alkyne architectures. Its pendant ethynyl group exhibits high reactivity in palladium-catalyzed cross-couplings, while the carboxylic acid functionality allows for direct derivatization or salt formation. The compound demonstrates excellent bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: