Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Chloro-1-(4-methoxyphenyl)ethanone

  • CAS No. 2196-99-8

  • Cat. No. CS-W016981
  • Purity≥98%
  • MDL No.MFCD00216508

*For research and further manufacturing use only, not for direct human use.

2-Chloro-1-(4-methoxyphenyl)ethanone|CS-W016981

Structure of 2196-99-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 2196-99-8
  • Cat. No. CS-W016981
  • Purity ≥98%
  • MDL No. MFCD00216508
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉ClO₂
  • Molecular Weight 184.62
  • Synonym(s) 4-Methoxyphenacyl Chloride
  • SMILES COC1=CC=C(C=C1)C(=O)CCl

Description

2-Chloro-1-(4-methoxyphenyl)ethanone features a chlorinated acetyl group attached to a para-methoxy-substituted phenyl ring, delivering enhanced electrophilicity for efficient C–C bond formation. This bench-stable ketone integrates readily into synthetic sequences requiring controlled reactivity and improved solubility in polar organic media.

Application

2-Chloro-1-(4-methoxyphenyl)ethanone serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of pharmaceutically relevant heterocycles and functionalized aryl ketones. Its ortho-chlorinated acetyl moiety facilitates electrophilic substitution and coupling reactions, while the para-methoxy group enhances solubility and provides a handle for further derivatization. Bench-stable and amenable to standard purification techniques, it functions reliably in multi-step syntheses requiring moderate reactivity and predictable transformation pathways.

Synthesis

  • Route1

    References

    • Prebil, Rok; Stavber, Stojan Advanced Synthesis and Catalysis, 2014 , vol. 356, # 6 p. 1266 - 1274
  • Route2
    • null|null
      100-66-3
    • null|null
      79-04-9
    • ~80%
    • In-stock
      2-Chloro-1-(4-methoxyphenyl)ethanone|CS-W016981
      2196-99-8

    References

    • Giordano, Claudio; Castaldi, Graziano; Casagrande, Francesco; Belli, Aldo Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 11 p. 2575 - 2582
  • Route3
    • null|null
      14337-31-6
    • ~90%
    • In-stock
      2-Chloro-1-(4-methoxyphenyl)ethanone|CS-W016981
      2196-99-8

    References

    • Ram, Ram N.; Manoj Journal of Organic Chemistry, 2008 , vol. 73, # 14 p. 5633 - 5635

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P260-P270-P280-P280

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.1167
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Chloro-1-(4-methoxyphenyl)ethanone sigma2-Chloro-1-(4-methoxyphenyl)ethanone manufacturer2-Chloro-1-(4-methoxyphenyl)ethanone price2-Chloro-1-(4-methoxyphenyl)ethanone structure2-Chloro-1-(4-methoxyphenyl)ethanone SDSbuy 2-Chloro-1-(4-methoxyphenyl)ethanone2-Chloro-1-(4-methoxyphenyl)ethanone supplier2-Chloro-1-(4-methoxyphenyl)ethanone uses2-Chloro-1-(4-methoxyphenyl)ethanone molecular weightprice of 2-Chloro-1-(4-methoxyphenyl)ethanone2-Chloro-1-(4-methoxyphenyl)ethanone chemical name formula of 2-Chloro-1-(4-methoxyphenyl)ethanone
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label