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Structure of 2212021-56-0
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This chiral piperidine derivative features a tert-butyl carbamate protecting group and a cyano-substituted methyl moiety, enabling straightforward functionalization at the 3-position. The molecule exhibits excellent stability under standard bench conditions and facilitates efficient access to complex nitrogen-containing scaffolds in medicinal chemistry applications.
(2S)-tert-Butyl 3-cyano-2-methyl-4-oxopiperidine-1-carboxylate serves as a versatile chiral building block for the synthesis of pyrrolidine and piperidine-based scaffolds. The molecule features a sterically hindered tertiary amine center, a masked aldehyde equivalent via the cyano group, and a carbonyl at C4, enabling diverse transformations including reductive amination, nucleophilic addition, and cyclization reactions. Its bench-stable nature and compatibility with standard protecting group manipulations make it ideal for medicinal chemistry campaigns requiring stereocontrolled access to nitrogen-containing heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: