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CS-W001157 4
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6-Bromobenzo[cd]indol-2(1H)-one

  • CAS No. 24856-00-6

  • Cat. No. CS-0435648
  • Molecule weight248.08
  • Purity≥95%
  • MDL No.MFCD00463109

*For research and further manufacturing use only, not for direct human use.

6-Bromobenzo[cd]indol-2(1H)-one|CS-0435648

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General Information

  • CAS No. 24856-00-6
  • Cat. No. CS-0435648
  • Purity ≥95%
  • MDL No. MFCD00463109
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₆BrNO
  • Molecular Weight 248.08
  • Synonym(s) 5-Bromo-8-naphtholactam
  • SMILES O=C1NC2=C3C1=CC=CC3=C(Br)C=C2

Description

6-Bromobenzo[cd]indol-2(1H)-one features a brominated indole core with a lactam functionality, offering a reactive handle for cross-coupling and functionalization. This electron-deficient scaffold integrates readily into complex heterocyclic systems under standard conditions.

Application

6-Bromobenzo[cd]indol-2(1H)-one serves as a versatile building block for the synthesis of polycyclic heterocycles and bioactive scaffolds. The bromine substituent enables palladium-catalyzed cross-coupling reactions, facilitating C–C bond formation under standard conditions. Its stability and compatibility with diverse functional groups make it well-suited for medicinal chemistry campaigns and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   3.168
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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