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2-(6-Oxo-1,6-dihydropyridazin-3-yl)acetic acid

  • CAS No. 261768-25-6

  • Cat. No. CS-0199664
  • Molecule weight154.12
  • Purity≥97%
  • MDL No.MFCD09754153

*For research and further manufacturing use only, not for direct human use.

2-(6-Oxo-1,6-dihydropyridazin-3-yl)acetic acid|CS-0199664

Structure of 261768-25-6

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General Information

  • CAS No. 261768-25-6
  • Cat. No. CS-0199664
  • Purity ≥97%
  • MDL No. MFCD09754153
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆N₂O₃
  • Molecular Weight 154.12
  • Synonym(s) None
  • SMILES O=C(O)CC(C=C1)=NNC1=O

Description

This pyridazinone-acetic acid derivative integrates a reactive ketone and carboxylic acid functional group, enabling direct conjugation or derivatization in synthetic workflows. The electron-deficient pyridazinone core enhances stability under standard conditions, while the pendant acetyl moiety facilitates modular assembly in bioconjugation and medicinal chemistry applications.

Application

2-(6-Oxo-1,6-dihydropyridazin-3-yl)acetic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridazinone-based heterocyclic scaffolds. Its α-acyl functionality facilitates nucleophilic substitution and condensation reactions, while the carboxylic acid group supports direct derivatization or salt formation. The compound exhibits good bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis campaigns in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   83.05
  • LogP   -0.603
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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