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Structure of 28383-57-5
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5-Bromo-1H-pyrrole-2-carboxylic acid integrates a bromine substituent at the 5-position and a carboxylic acid group at the 2-position of the pyrrole ring. This configuration imparts enhanced electrophilicity and facilitates downstream functionalization via cross-coupling or derivatization. The compound exhibits good solubility in common organic solvents and stability under standard bench conditions, enabling efficient use in synthetic routes for bioactive heterocycles and pharmaceutical intermediates.
5-Bromo-1H-pyrrole-2-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling direct functionalization at the C5 position via palladium-catalyzed cross-coupling reactions. The carboxylic acid group facilitates derivatization through amide formation or esterification, while the bromine atom provides orthogonal reactivity for further diversification. Bench-stable and compatible with standard purification methods, it functions reliably in the construction of complex pyrrole-based scaffolds used in agrochemical and pharmaceutical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: