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Structure of 301185-41-1
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tert-Butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate features a propargyl group attached to the piperidine nitrogen, enabling facile conjugation via click chemistry. This bench-stable, moisture-tolerant building block integrates readily into bioactive scaffolds and facilitates rapid diversification in medicinal chemistry campaigns.
tert-Butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate serves as a versatile building block for the synthesis of piperidine-containing scaffolds, enabling efficient access to functionalized heterocycles via Cu-catalyzed azide-alkyne cycloaddition (CuAAC). The propargyl group provides a reliable handle for click chemistry, while the tert-butoxycarbonyl (Boc) group offers robust protection under standard conditions. Its bench-stable nature and compatibility with diverse reaction environments facilitate straightforward purification and integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: