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Structure of 32936-76-8
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1-Methylcyclobutanecarboxylic acid features a rigid cyclobutane ring with a methyl-substituted carboxylic acid group, delivering enhanced steric definition and metabolic stability. This structural motif integrates readily into bioactive scaffolds, offering improved lipophilicity and conformational constraint for medicinal chemistry applications.
1-Methylcyclobutanecarboxylic acid serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering a rigid, substituted cyclobutane scaffold with enhanced metabolic stability. The carboxylic acid functionality enables direct derivatization to amides, esters, and acyl chlorides, while the adjacent methyl group provides steric differentiation and improved lipophilicity. Its bench-stable nature and compatibility with standard coupling reagents facilitate integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: