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Structure of 347389-74-6
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2-Ethynyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane features a boronate ester group paired with a terminal alkyne, enabling direct coupling in palladium-catalyzed reactions. This bench-stable reagent integrates cleanly into click chemistry and Suzuki-Miyaura protocols, delivering efficient access to functionalized alkynyl architectures with minimal side reactions.
2-Ethynyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boron source for palladium-catalyzed coupling reactions. Its tetramethyl-substituted dioxaborolane ring enhances air and moisture stability while enabling efficient Suzuki-Miyaura cross-coupling with aryl, vinyl, and heteroaryl halides. The terminal alkyne functionality allows for direct incorporation into conjugated frameworks, facilitating the synthesis of functionalized alkynes and extended π-systems under mild conditions.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: