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CS-W001157 4
Total: USD 88.00

2-Chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide

  • CAS No. 371219-74-8

  • Cat. No. CS-0065297
  • Molecule weight262.73
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide|CS-0065297

Structure of 371219-74-8

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General Information

  • CAS No. 371219-74-8
  • Cat. No. CS-0065297
  • Purity ≥96%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₅ClN₂O
  • Molecular Weight 262.73
  • Synonym(s) 2-Chloro-5,6,7,8,9,10-hexahydro-cyclohepta[b]indole-6-carboxylic acid amide
  • SMILES O=C(C1CCCCC2=C1NC3=C2C=C(Cl)C=C3)N

Synthesis

  • Route1
    • null|null
      871586-90-2
    • ~21%
    • 2-Chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide|CS-0065297
      371219-74-8

    References

    • ELIXIR PHARMACEUTICALS, INC.; CURTIS, Rory; DISTEFANO, Peter Patent: WO2010/54382 A1, 2010 ; Location in patent: Page/Page column 58 ;
  • Route2
    • null|null
      871586-89-9
    • ~%
    • 2-Chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide|CS-0065297
      371219-74-8

    References

    • Napper, Andrew D.; Hixon, Jeffrey; McDonagh, Thomas; Keavey, Kenneth; Pons, Jean-Francois; Barker, Jonathan; Yau, Wei Tsung; Amouzegh, Patricia; Flegg, Adam; Hamelin, Estelle; Thomas, Russell J.; Kates, Michael; Jones, Stephen; Navia, Manuel A.; Saunders, Jeffrey O.; DiStefano, Peter S.; Curtis, Rory Journal of Medicinal Chemistry, 2005 , vol. 48, # 25 p. 8045 - 8054
  • Route3

    References

    • Napper, Andrew D.; Hixon, Jeffrey; McDonagh, Thomas; Keavey, Kenneth; Pons, Jean-Francois; Barker, Jonathan; Yau, Wei Tsung; Amouzegh, Patricia; Flegg, Adam; Hamelin, Estelle; Thomas, Russell J.; Kates, Michael; Jones, Stephen; Navia, Manuel A.; Saunders, Jeffrey O.; DiStefano, Peter S.; Curtis, Rory Journal of Medicinal Chemistry, 2005 , vol. 48, # 25 p. 8045 - 8054

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   58.88
  • LogP   3.1166
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   1

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