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Structure of 40003-41-6
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2-Bromo-4-methylthiazole-5-carboxylic acid features a brominated thiazole core with a carboxylic acid at the C5 position, enabling direct conjugation in heterocyclic synthesis. The methyl group enhances electronic stability, while the bromine serves as a reactive handle for cross-coupling transformations under standard conditions. This compound integrates readily into bioactive molecule scaffolds requiring halogenated heterocycles.
2-Bromo-4-methylthiazole-5-carboxylic acid serves as a versatile building block for thiazole-based scaffolds in medicinal chemistry and agrochemical synthesis. Its bromine and carboxylic acid functionalities enable direct coupling reactions, including Suzuki-Miyaura and Stille couplings, and facilitate derivatization via amide formation or esterification. The molecule exhibits good bench stability and facilitates purification by recrystallization, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H317
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Precautionary Statements : P261-P272-P280-P302+P352-P363-P501
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Lot numbers can be found on the outside label of a product: