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CS-W001157 4
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4-Bromo-7-methoxy-1H-pyrrolo[2,3-c]pyridine

  • CAS No. 425380-37-6

  • Cat. No. CS-W000125
  • Molecule weight227.06
  • Purity≥97%
  • MDL No.MFCD11845544

*For research and further manufacturing use only, not for direct human use.

4-Bromo-7-methoxy-1H-pyrrolo[2,3-c]pyridine|CS-W000125

Structure of 425380-37-6

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General Information

  • CAS No. 425380-37-6
  • Cat. No. CS-W000125
  • Purity ≥97%
  • MDL No. MFCD11845544
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇BrN₂O
  • Molecular Weight 227.06
  • Synonym(s) bromomethoxypyrrolocpyridine
  • SMILES COC1=NC=C(Br)C2=C1NC=C2

Description

4-Bromo-7-methoxy-1H-pyrrolo[2,3-c]pyridine features a fused heterocyclic core with complementary electronic properties, enabling efficient coupling in cross-coupling reactions. The bromo group serves as a reliable handle for palladium-catalyzed transformations, while the methoxy substituent enhances solubility and modulates reactivity. This bench-stable scaffold supports rapid diversification in medicinal chemistry and materials science applications.

Application

4-Bromo-7-methoxy-1H-pyrrolo[2,3-c]pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined halogen reactivity. The methoxy group enhances solubility and modulates electronic properties, while the pyrrolopyridine core provides a rigid, planar scaffold suitable for targeted heterocyclic synthesis. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient incorporation into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.91
  • LogP   2.334
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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