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Structure of 42856-71-3
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(S)-2-Methylpyrrolidine-2-carboxylic acid is a chiral, non-proteinogenic amino acid featuring a rigid pyrrolidine ring and a stereodefined methyl substituent. This configuration imparts enhanced conformational stability and favorable solubility in polar solvents. The carboxylic acid group enables direct coupling in peptide synthesis or derivatization for medicinal chemistry applications.
(S)-2-Methylpyrrolidine-2-carboxylic acid serves as a valuable chiral building block in medicinal chemistry, offering a rigid, stereodefined pyrrolidine core with enhanced metabolic stability. Its carboxylic acid functionality enables direct amidation, esterification, and coupling reactions, while the adjacent quaternary stereocenter provides excellent stereochemical control in peptide-like scaffold construction. The compound exhibits good bench stability and facilitates efficient purification via standard chromatographic methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: