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CS-W001157 4
Total: USD 88.00

Nabumetone

  • CAS No. 42924-53-8

  • Cat. No. CS-2669
  • Molecule weight228.29
  • Purity≥98%
  • MDL No.MFCD00079518

*For research and further manufacturing use only, not for direct human use.

Nabumetone|CS-2669

Structure of 42924-53-8

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General Information

  • CAS No. 42924-53-8
  • Cat. No. CS-2669
  • Purity ≥98%
  • MDL No. MFCD00079518
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₆O₂
  • Molecular Weight 228.29
  • Synonym(s) BRL14777
  • SMILES CC(CCC1=CC=C2C=C(OC)C=CC2=C1)=O

Application

Nabumetone serves as a well-established nonsteroidal anti-inflammatory agent, functioning as a prodrug that undergoes metabolic activation to yield the active 6-methoxy-2-naphthylacetic acid metabolite. Its structure enables selective cyclooxygenase-2 inhibition with reduced gastrointestinal toxicity compared to traditional NSAIDs. The compound exhibits good bench stability and compatibility with standard synthetic workflows, facilitating its use in medicinal chemistry optimization and API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H320
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P362

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   3.37
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

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