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Structure of 4522-35-4
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3-Iodo-1H-pyrazole is a bench-stable heterocyclic iodide featuring a reactive iodo substituent at the 3-position of the pyrazole ring. This configuration enables direct functionalization in cross-coupling reactions, facilitating efficient access to diverse nitrogen-containing scaffolds. The molecule’s electron-deficient nature enhances its utility in transition-metal-catalyzed transformations, particularly under mild conditions.
3-Iodo-1H-pyrazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl and heteroaryl scaffolds. Its iodine substituent provides high reactivity in standard Suzuki, Stille, and Negishi transformations, while the pyrazole core offers excellent functional group tolerance and bench stability, facilitating efficient synthesis of complex nitrogen-containing architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P301+P310-P330-P501
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Lot numbers can be found on the outside label of a product: