2,5-Dimethylcelecoxib

CAS No. 457639-26-8
Cat. No. CS-W011711
Molecule weight395.40
Purity≥98%
MDL No.MFCD19443858

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 457639-26-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 457639-26-8
Cat. No. CS-W011711
Purity ≥98%
MDL No. MFCD19443858
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₈H₁₆F₃N₃O₂S
Molecular Weight 395.40
Synonym(s) 4-(5-(2,5-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
SMILES O=S(C1=CC=C(N2N=C(C(F)(F)F)C=C2C3=CC(C)=CC=C3C)C=C1)(N)=O

Application

2,5-Dimethyl-celecoxib (CAS 457639-26-8) blocks prostaglandin E2 synthesis by selectively inhibiting cyclooxygenase-2 activity while modulating transforming growth factor-β2 signaling. It suppresses COX-2 expression in inflammatory pathways. Researchers use this compound to probe pro-oxidative stress mechanisms in metastatic melanoma and breast cancer cells, revealing its potential cytotoxic effects. Its interaction with silymarin in rat osteoarthritis models further highlights synergistic anti-inflammatory action.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 77.98
LogP 3.82234
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 3

Other Classifications

Bioactive Molecules Bioactive Small Molecules

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Sulfonamide

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2,5-Dimethylcelecoxib sigma2,5-Dimethylcelecoxib manufacturer2,5-Dimethylcelecoxib price2,5-Dimethylcelecoxib structure2,5-Dimethylcelecoxib SDSbuy 2,5-Dimethylcelecoxib2,5-Dimethylcelecoxib supplier2,5-Dimethylcelecoxib uses2,5-Dimethylcelecoxib molecular weightprice of 2,5-Dimethylcelecoxib2,5-Dimethylcelecoxib chemical name formula of 2,5-Dimethylcelecoxib

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,5-Dimethylcelecoxib

CAS No. 457639-26-8

Recommended Products