Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2,4-Dichloro-5-nitropyrimidine

  • CAS No. 49845-33-2

  • Cat. No. CS-W009121
  • Purity≥97%
  • MDL No.MFCD00127867

*For research and further manufacturing use only, not for direct human use.

2,4-Dichloro-5-nitropyrimidine|CS-W009121

Structure of 49845-33-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 49845-33-2
  • Cat. No. CS-W009121
  • Purity ≥97%
  • MDL No. MFCD00127867
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄HCl₂N₃O₂
  • Molecular Weight None
  • Synonym(s) 2,4-Dichloro-5-nitropyrimidine
  • SMILES ClC1=NC=C([N+]([O-])=O)C(Cl)=N1

Application

2,4-Dichloro-5-nitropyrimidine serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyrimidines via nucleophilic aromatic substitution. The dichloro substituents provide orthogonal reactivity for sequential functionalization, while the nitro group offers a handle for reduction and further derivatization. Its bench-stable nature and compatibility with standard reaction conditions make it a practical choice for medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Hansen, Finn K.; Geffken, Detlef Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 2 p. 321 - 328
  • Route2
    • In-stock
      5-Nitrouracil|CS-W017981
      611-08-5
    • null|null
      10025-87-3
    • ~%
    • In-stock
      2,4-Dichloro-5-nitropyrimidine|CS-W009121
      49845-33-2

    References

    • DuPont Pharmaceuticals Company Patent: US6342503 B1, 2002 ; Location in patent: Example 105 ; US 6342503 B1
  • Route3
    • In-stock
      5-Nitrouracil|CS-W017981
      611-08-5
    • null|null
      7647-01-0
    • null|null
      10025-87-3
    • ~%
    • In-stock
      2,4-Dichloro-5-nitropyrimidine|CS-W009121
      49845-33-2

    References

    • Isay Chemische Berichte, 1906 , vol. 39, p. 252

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   68.92
  • LogP   1.6916
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2,4-Dichloro-5-nitropyrimidine sigma2,4-Dichloro-5-nitropyrimidine manufacturer2,4-Dichloro-5-nitropyrimidine price2,4-Dichloro-5-nitropyrimidine structure2,4-Dichloro-5-nitropyrimidine SDSbuy 2,4-Dichloro-5-nitropyrimidine2,4-Dichloro-5-nitropyrimidine supplier2,4-Dichloro-5-nitropyrimidine uses2,4-Dichloro-5-nitropyrimidine molecular weightprice of 2,4-Dichloro-5-nitropyrimidine2,4-Dichloro-5-nitropyrimidine chemical name formula of 2,4-Dichloro-5-nitropyrimidine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label