TCEP hydrochloride

CAS No. 51805-45-9
Cat. No. CS-W012216
Purity≥97%
MDL No.MFCD00145469

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 51805-45-9

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Reducing persistent water-soluble disulfides at pH 4.5 within five minutes, Tris(2-carboxyethyl)phosphine hydrochloride solution (CAS 51805-45-9) maintains reductive potency across pH 1.5–8.5 and resists air oxidation more effectively than DTT.

Application

Tris(2-carboxyethyl)phosphine hydrochloride (CAS 51805-45-9) drives peptide and protein desulfurization by enabling efficient diboron-mediated transformations in complex reaction systems. It stabilizes thiol groups under physiological conditions. Researchers leverage this property to enhance thiol-Michael additions in electrospun scaffolds, improve sperm head lysis for RNA isolation, enable chiral cystine differentiation via peroxidase-mimicking assays, and boost accuracy in in situ cell digestion for proteomics workflows.

General Information

CAS No. 51805-45-9
Cat. No. CS-W012216
Purity ≥97%
MDL No. MFCD00145469
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₆ClO₆P
Molecular Weight 286.65
Synonym(s) Tris(2-carboxyethyl)phosphine hydrochloride
SMILES O=C(O)CCP(CCC(O)=O)CCC(O)=O.Cl

Computational Chemistry Data

TPSA 111.9
LogP 1.3142
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 9

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 3261
Class : 8	Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Life Science Biochemicals Reductant

General Reagents Reductive Reagents Other Reductive Reagents

Catalysts and Ligands Ligands Achiral Mono/Dual Phosphorus Ligands Alkyl Phosphorus(Monophosphorus) Ligands

Chemical Biology Pharmaceutical Development and Drug Discovery Research Bioconjugation Functionality Creating Reagents

Chemical Biology Linkers and Crosslinkers Heterobifunctional Cross-Linkers

Biochemistry Biochemicals and Reagents Bioconjugation Functionality Creating Reagents

Biochemistry Biochemicals and Reagents Bioconjugation Heterobifunctional Cross-Linkers

Chemical Synthesis Synthetic Reagents Reduction Reduction Reagents (Other)

Catalysis Cross-Coupling Phosphine Ligands

Catalysis Cross-coupling Reaction using Transition Metal Catalysts Phosphine Ligands

Key Words

TCEP hydrochloride sigmaTCEP hydrochloride manufacturerTCEP hydrochloride priceTCEP hydrochloride structureTCEP hydrochloride SDSbuy TCEP hydrochlorideTCEP hydrochloride supplierTCEP hydrochloride usesTCEP hydrochloride molecular weightprice of TCEP hydrochlorideTCEP hydrochloride chemical name formula of TCEP hydrochloride

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

TCEP hydrochloride

CAS No. 51805-45-9

Recommended Products