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CS-W001157 4
Total: USD 88.00

4-(Bromomethyl)-1-methyl-1H-pyrazole hydrobromide

  • CAS No. 528878-44-6

  • Cat. No. CS-0051173
  • Molecule weight255.94
  • Purity≥95%
  • MDL No.MFCD13195912

*For research and further manufacturing use only, not for direct human use.

4-(Bromomethyl)-1-methyl-1H-pyrazole hydrobromide|CS-0051173

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General Information

  • CAS No. 528878-44-6
  • Cat. No. CS-0051173
  • Purity ≥95%
  • MDL No. MFCD13195912
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈Br₂N₂
  • Molecular Weight 255.94
  • Synonym(s) 4-(broMoMethyl)-1-Methyl-1H-Pyrazole hydrobroMide 1-Methyl-, MonohydrobroMide
  • SMILES CN1C=C(C=N1)CBr.Br

Description

This bromomethyl-functionalized pyrazole derivative features a reactive alkylating handle ideal for conjugation workflows. The hydrobromide salt enhances solubility and stability under standard conditions, enabling efficient incorporation into bioconjugates and synthetic intermediates.

Application

4-(Bromomethyl)-1-methyl-1H-pyrazole hydrobromide serves as a versatile building block for constructing pyrazole-based scaffolds in medicinal chemistry and agrochemical development. The bromomethyl group enables efficient nucleophilic substitution and cross-coupling reactions, while the pyrazole core offers moderate stability and compatibility with common protecting group strategies. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthetic workflows requiring functional group diversity.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   17.82
  • LogP   1.8929
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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