4-Bromo-2-hydroxybenzamide

CAS No. 5428-40-0
Cat. No. CS-0119943
Purity≥97%
MDL No.MFCD07780674

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 5428-40-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

4-Bromo-2-hydroxybenzamide features a bromine atom at the para position relative to the amide group, combined with a phenolic hydroxyl for enhanced reactivity. This electron-deficient aromatic scaffold enables efficient coupling in cross-coupling and peptide synthesis workflows. The molecule exhibits excellent stability under standard bench conditions and facilitates direct functionalization of complex heterocycles.

Application

4-Bromo-2-hydroxybenzamide serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via Ullmann-type couplings or electrophilic substitution. The ortho-hydroxyl group facilitates in situ activation for palladium-catalyzed cross-coupling, while the bromide supports reliable Suzuki and Stille reactions. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses requiring orthogonal reactivity and functional group compatibility.

General Information

CAS No. 5428-40-0
Cat. No. CS-0119943
Purity ≥97%
MDL No. MFCD07780674
Storage RT, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆BrNO₂
Molecular Weight 216.03
Synonym(s) Benzamide,4-bromo-2-hydroxy
SMILES O=C(N)C1=CC=C(Br)C=C1O

Computational Chemistry Data

TPSA 63.32
LogP 1.2536
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Amide

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

4-Bromo-2-hydroxybenzamide sigma4-Bromo-2-hydroxybenzamide manufacturer4-Bromo-2-hydroxybenzamide price4-Bromo-2-hydroxybenzamide structure4-Bromo-2-hydroxybenzamide SDSbuy 4-Bromo-2-hydroxybenzamide4-Bromo-2-hydroxybenzamide supplier4-Bromo-2-hydroxybenzamide uses4-Bromo-2-hydroxybenzamide molecular weightprice of 4-Bromo-2-hydroxybenzamide4-Bromo-2-hydroxybenzamide chemical name formula of 4-Bromo-2-hydroxybenzamide

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Bromo-2-hydroxybenzamide

CAS No. 5428-40-0

Recommended Products