Z-Asp(OtBu)-OH

CAS No. 5545-52-8
Cat. No. CS-W011994
Purity≥98%
MDL No.MFCD00042857

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 5545-52-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Z-Asp(OtBu)-OH is a protected aspartic acid derivative featuring a benzyloxycarbonyl (Z) group at the α-amino position and a tert-butyl ester at the side-chain carboxyl. This configuration enables stable incorporation into peptide chains under standard coupling conditions, with orthogonal deprotection compatibility for sequential synthesis. The Z group facilitates purification and handling during solid-phase peptide synthesis workflows.

Application

Z-Asp(OtBu)-OH serves as a key dipeptide building block in peptide synthesis, enabling efficient formation of C-terminal protected aspartic acid residues. The Z (benzyloxycarbonyl) group provides stable N-protection, while the OtBu (tert-butyl ester) offers orthogonal protection for the side-chain carboxylate. This combination facilitates selective coupling reactions, excellent bench stability, and straightforward deprotection under standard conditions, making it ideal for the synthesis of complex peptide sequences and peptidomimetics.

General Information

CAS No. 5545-52-8
Cat. No. CS-W011994
Purity ≥98%
MDL No. MFCD00042857
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₆H₂₁NO₆
Molecular Weight 323.34
Synonym(s) None
SMILES CC(C)(C)OC(C[C@@H](C(O)=O)NC(OCC1=CC=CC=C1)=O)=O

Computational Chemistry Data

TPSA 101.93
LogP 2.0978
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Aspartic acid and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

Key Words

Z-Asp(OtBu)-OH sigmaZ-Asp(OtBu)-OH manufacturerZ-Asp(OtBu)-OH priceZ-Asp(OtBu)-OH structureZ-Asp(OtBu)-OH SDSbuy Z-Asp(OtBu)-OHZ-Asp(OtBu)-OH supplierZ-Asp(OtBu)-OH usesZ-Asp(OtBu)-OH molecular weightprice of Z-Asp(OtBu)-OHZ-Asp(OtBu)-OH chemical name formula of Z-Asp(OtBu)-OH

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Z-Asp(OtBu)-OH

CAS No. 5545-52-8

Recommended Products