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Structure of 57798-00-2
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8-Bromoquinoline-4-ol features a brominated quinoline core with a phenolic hydroxyl group, delivering enhanced reactivity in metal-catalyzed cross-coupling reactions. This bench-stable compound integrates seamlessly into synthetic pathways requiring electron-deficient heterocycles, enabling efficient access to functionalized scaffolds in medicinal chemistry and materials science.
8-Bromoquinoline-4-ol serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling direct functionalization at the C4 position via palladium-catalyzed cross-coupling. Its bromine moiety provides high reactivity in Suzuki, Stille, and Negishi reactions, while the phenolic hydroxyl group offers orthogonal handling for derivatization or metal complexation. The compound exhibits good bench stability and facilitates purification by recrystallization, making it well-suited for scalable synthesis of quinoline-based pharmaceuticals and ligands.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H301-H318
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Precautionary Statements : P264-P270-P280-P330-P405-P501
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Lot numbers can be found on the outside label of a product: