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Structure of 580-21-2
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2-Fluoroquinoline serves as a pivotal heterocyclic scaffold in medicinal chemistry, featuring a fluorine atom at the 2-position that enhances metabolic stability and modulates electronic properties. This electron-deficient core integrates readily into bioactive molecules, enabling efficient coupling reactions and serving as a key building block for pharmaceuticals and functional materials.
2-Fluoroquinoline serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling efficient late-stage fluorination and transition-metal-catalyzed coupling reactions. Its electron-deficient aromatic core enhances reactivity in Pd- and Ni-mediated cross-couplings, while the fluoro substituent provides favorable metabolic stability and modulates electronic properties. Bench-stable and readily purified, it functions effectively in diverse synthetic workflows for heterocyclic scaffold elaboration.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P264-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: