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CS-W001157 4
Total: USD 88.00

3-(2-Thienyl)propanoic acid

  • CAS No. 5928-51-8

  • Cat. No. CS-0043395
  • Molecule weight156.21
  • Purity≥97%
  • MDL No.MFCD00047093

*For research and further manufacturing use only, not for direct human use.

3-(2-Thienyl)propanoic acid|CS-0043395

Structure of 5928-51-8

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General Information

  • CAS No. 5928-51-8
  • Cat. No. CS-0043395
  • Purity ≥97%
  • MDL No. MFCD00047093
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈O₂S
  • Molecular Weight 156.21
  • Synonym(s) None
  • SMILES O=C(O)CCC1=CC=CS1

Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standardsThese Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Application

3-(2-Thienyl)propanoic acid serves as a versatile building block for synthesizing bioactive heterocycles and pharmaceutical intermediates. Its conjugated thienyl-alkyl carboxylic acid structure enables reliable coupling reactions, including amide formation and esterification, with excellent functional group tolerance. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1

    References

    • Warner-Lambert Company Patent: US6710190 B1, 2004 ; Location in patent: Page column 17 ;
  • Route2

    References

    • Brown, Thomas H.; Blakemore, Robert C.; Blurton, Peter; Durant, Graham J.; Ganellin, C. Robin; et al. European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 65 - 72
  • Route3
    • null|null
      1003-09-4
    • null|null
      3984-22-3
    • ~77%
    • In-stock
      3-(2-Thienyl)propanoic acid|CS-0043395
      5928-51-8

    References

    • Lemhadri, Mhamed; Doucet, Henri; Santelli, Maurice Tetrahedron, 2004 , vol. 60, # 50 p. 11533 - 11540

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.7653
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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