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Structure of 604000-99-9
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4-Formyl-3-nitrobenzoic acid features a conjugated system integrating electron-deficient nitro and formyl groups flanking a carboxylic acid handle. This arrangement enables direct coupling in amide formation, facilitates metal-catalyzed cross-coupling reactions, and supports derivatization for probe design in chemical biology applications.
4-Formyl-3-nitrobenzoic acid serves as a versatile bifunctional building block for medicinal chemistry and materials synthesis, enabling direct access to functionalized heterocycles and conjugated systems. The ortho-directed nitro and formyl groups facilitate sequential transformations, including reductive amination, condensation reactions, and transition-metal-catalyzed couplings. Its bench-stable crystalline form allows straightforward handling and purification, while the electron-withdrawing nitro group enhances electrophilicity at the formyl position, promoting efficient derivatization under mild conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: