5-Chloro-1H-pyrazolo[4,3-d]pyrimidine

CAS No. 633328-98-0
Cat. No. CS-0045848
Purity≥95%
MDL No.MFCD18251003

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Chloro-1H-pyrazolo[4,3-d]pyrimidine|CS-0045848

Structure of 633328-98-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Chloro-1H-pyrazolo[4,3-d]pyrimidine is a heterocyclic scaffold featuring a chlorine atom at the 5-position, enabling direct functionalization in medicinal chemistry. This electron-deficient core integrates readily into kinase inhibitors and antiviral agents, offering high reactivity under standard coupling conditions. The pyrazolopyrimidine framework provides structural rigidity and enhanced binding affinity in target-directed synthesis.

Application

5-Chloro-1H-pyrazolo[4,3-d]pyrimidine serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. Its chloro substituent enables palladium-catalyzed cross-coupling reactions, facilitating the construction of diverse biaryl and aryl-substituted scaffolds. The core pyrazolopyrimidine framework exhibits excellent bench stability and compatibility with common functional groups, enabling efficient incorporation into complex molecular architectures through standard synthetic protocols.

General Information

CAS No. 633328-98-0
Cat. No. CS-0045848
Purity ≥95%
MDL No. MFCD18251003
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃ClN₄
Molecular Weight 154.56
Synonym(s) 5-Chloropyrazolo[4,3-d]pyrimidine
SMILES ClC1=NC=C(NN=C2)C2=N1

Computational Chemistry Data

TPSA 54.46
LogP 1.0063
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Drug Discovery Cancer USP1

Key Words

5-Chloro-1H-pyrazolo[4,3-d]pyrimidine sigma5-Chloro-1H-pyrazolo[4,3-d]pyrimidine manufacturer5-Chloro-1H-pyrazolo[4,3-d]pyrimidine price5-Chloro-1H-pyrazolo[4,3-d]pyrimidine structure5-Chloro-1H-pyrazolo[4,3-d]pyrimidine SDSbuy 5-Chloro-1H-pyrazolo[4,3-d]pyrimidine5-Chloro-1H-pyrazolo[4,3-d]pyrimidine supplier5-Chloro-1H-pyrazolo[4,3-d]pyrimidine uses5-Chloro-1H-pyrazolo[4,3-d]pyrimidine molecular weightprice of 5-Chloro-1H-pyrazolo[4,3-d]pyrimidine5-Chloro-1H-pyrazolo[4,3-d]pyrimidine chemical name formula of 5-Chloro-1H-pyrazolo[4,3-d]pyrimidine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Chloro-1H-pyrazolo[4,3-d]pyrimidine

CAS No. 633328-98-0

Recommended Products