Benzene-1,2,4,5-tetraol

CAS No. 636-32-8
Cat. No. CS-0095053
Purity≥97%
MDL No.MFCD19441381

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 636-32-8

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Description

Benzene-1,2,4,5-tetraol features four hydroxyl groups arranged in a symmetric pattern on the aromatic ring, conferring high polarity and enhanced solubility in aqueous media. This configuration imparts strong hydrogen-bonding capacity and stability under ambient conditions, enabling reliable use in synthetic transformations requiring controlled reactivity.

Application

Benzene-1,2,4,5-tetraol serves as a versatile polyol building block for the synthesis of complex heterocycles and functionalized aromatic systems. Its four hydroxyl groups enable sequential derivatization and orthogonal protection strategies, facilitating access to diversified scaffolds in medicinal chemistry. The compound exhibits sufficient bench stability for routine handling and is compatible with standard coupling and oxidation protocols.

General Information

CAS No. 636-32-8
Cat. No. CS-0095053
Purity ≥97%
MDL No. MFCD19441381
Storage -20°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆O₄
Molecular Weight 142.11
Synonym(s) 1,2,4,5-Benzenetetrol
SMILES OC1=CC(O)=C(O)C=C1O

Computational Chemistry Data

TPSA 80.92
LogP 0.509
H_Acceptors 4
H_Donors 4
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Material Science Covalent Organic Frameworks Other COFs Linkers

Material Science Material Building Blocks Covalent Organic Frameworks (COFs) Linkers Linkers (Others)

Material Science Polymer/Macromolecule Reagents Covalent Organic Frameworks (COFs) Linkers Linkers (Others)

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Benzene-1,2,4,5-tetraol

CAS No. 636-32-8

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