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CS-W001157 4
Total: USD 88.00

4-Methyloxazole

  • CAS No. 693-93-6

  • Cat. No. CS-0028372
  • Molecule weight83.09
  • Purity≥98%
  • MDL No.MFCD11110237

*For research and further manufacturing use only, not for direct human use.

4-Methyloxazole|CS-0028372

Structure of 693-93-6

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General Information

  • CAS No. 693-93-6
  • Cat. No. CS-0028372
  • Purity ≥98%
  • MDL No. MFCD11110237
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅NO
  • Molecular Weight 83.09
  • Synonym(s) 4-methyl-1,3-oxazole
  • SMILES CC1=COC=N1

Description

4-Methyloxazole is a heterocyclic compound featuring a five-membered ring with oxygen and nitrogen atoms, bearing a methyl group at the 4-position. This substitution enhances electron density at the ring’s C5 position, promoting reactivity in electrophilic aromatic substitution and facilitating use in synthetic routes to bioactive molecules. The compound exhibits good thermal stability and handles well under standard bench conditions.

Application

4-Methyloxazole serves as a versatile heterocyclic building block in synthetic organic chemistry, offering enhanced stability and predictable reactivity in electrophilic substitution and transition-metal-catalyzed coupling reactions. Its methyl group provides a site for selective functionalization, while the oxazole core exhibits favorable compatibility with common protecting groups and reaction conditions, enabling efficient access to complex scaffolds in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • US4039554 A1, ;
  • Route2
    • null|null
      4128-31-8
    • In-stock
      Hydroxyacetone|CS-0017823
      116-09-6
    • ~%
    • In-stock
      4-Methyloxazole|CS-0028372
      693-93-6

    References

    • US4039554 A1, ;
  • Route3

    References

    • US4039554 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅱ
Hazard Statements : H225-H318
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.03
  • LogP   0.98302
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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