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CS-W001157 4
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4-(4-(4-Methoxyphenyl)piperazin-1-yl)aniline Posaconazole Impurity

  • CAS No. 74852-62-3

  • Cat. No. CS-0228876
  • Molecule weight283.37
  • Purity≥98%
  • MDL No.MFCD02071496

*For research and further manufacturing use only, not for direct human use.

4-(4-(4-Methoxyphenyl)piperazin-1-yl)aniline Posaconazole Impurity|CS-0228876

Structure of 74852-62-3

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General Information

  • CAS No. 74852-62-3
  • Cat. No. CS-0228876
  • Purity ≥98%
  • MDL No. MFCD02071496
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₁N₃O
  • Molecular Weight 283.37
  • Synonym(s) 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline
  • SMILES NC1=CC=C(N2CCN(C3=CC=C(OC)C=C3)CC2)C=C1

Synthesis

  • Route1
    • Itraconazole impurity 17|CS-0130126
      74852-61-2
    • ~99%
    • 4-(4-(4-Methoxyphenyl)piperazin-1-yl)aniline Posaconazole Impurity|CS-0228876
      74852-62-3

    References

    • Shi, Wei; Nacev, Benjamin A.; Bhat, Shridhar; Liu, Jun O. ACS Medicinal Chemistry Letters, 2010 , vol. 1, # 4 p. 155 - 159
  • Route2
    • 1-(4-Methoxyphenyl)piperazine Miconazole  Impurity|CS-0229176
      38212-30-5
    • ~%
    • 4-(4-(4-Methoxyphenyl)piperazin-1-yl)aniline Posaconazole Impurity|CS-0228876
      74852-62-3

    References

    • Journal of Medicinal Chemistry, , vol. 27, # 7 p. 894 - 900
  • Route3
    • null|null
      100-00-5
    • ~%
    • 4-(4-(4-Methoxyphenyl)piperazin-1-yl)aniline Posaconazole Impurity|CS-0228876
      74852-62-3

    References

    • Journal of Medicinal Chemistry, , vol. 27, # 7 p. 894 - 900

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   41.73
  • LogP   2.604
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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