L-Prolinamide

CAS No. 7531-52-4
Cat. No. CS-D1209
Purity≥95%
MDL No.MFCD00005253

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Structure of 7531-52-4

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Description

L-Prolinamide features a stable pyrrolidine ring with a primary amide functional group, offering enhanced solubility and reactivity in peptide synthesis. This configuration enables efficient coupling under standard conditions, while the amide moiety supports hydrogen bonding in catalytic and supramolecular applications.

Application

L-Prolinamide serves as a versatile chiral building block in synthetic organic chemistry, enabling stereoselective transformations through its amide functionality and constrained pyrrolidine ring. Its bench-stable nature and compatibility with common coupling conditions facilitate efficient peptide and heterocycle synthesis. Functions effectively as a catalyst precursor and scaffold component in medicinal chemistry applications requiring defined stereochemistry and moderate polarity.

General Information

CAS No. 7531-52-4
Cat. No. CS-D1209
Purity ≥95%
MDL No. MFCD00005253
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₀N₂O
Molecular Weight 114.15
Synonym(s) None
SMILES NC([C@H]1NCCC1)=O

Computational Chemistry Data

TPSA 55.12
LogP -0.7763
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Proline and derivatives

Catalysts and Ligands Ligands Diamine Ligands Alkyl Diamine Ligands

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids Amino Acid Amides

Catalysis Asymmetric Synthesis Chiral Catalysts, Chiral Ligands, Chiral Reagents Proline-Based Organocatalysts

Catalysis Organocatalysts Asymmetric Organocatalysts

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L-Prolinamide

CAS No. 7531-52-4

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