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Structure of 80-18-2
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Methyl benzenesulfonate can be used asa methylation agent:For the C-methylation of perbromothiophene tosynthesize tribromo-methyl thiophene in the presence of butyllithium.In the nickel-catalyzedmethylation of unactivated alkyl halides and acid chlorides to prepare methylatedalkanes and ketones.It can alsobe used as a reactant in the etherification of sophoridinol derivatives tosynthesize N-substituted sophoridinic methyl ether derivatives.
Methyl benzenesulfonate serves as a reliable sulfonate ester reagent for nucleophilic substitution reactions, enabling efficient conversion of alcohols to more reactive intermediates. Its bench-stable nature and compatibility with a range of nucleophiles make it well-suited for use in coupling protocols and heterocycle synthesis. The arylsulfonyl group provides excellent leaving group ability while maintaining stability under standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314-H317-H318
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Precautionary Statements : P260-P280-P338-P351
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Lot numbers can be found on the outside label of a product: