Boc-L-Pyroglutaminol

CAS No. 81658-25-5
Cat. No. CS-W022605
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Structure of 81658-25-5

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Description

Boc-L-Pyroglutaminol serves as a protected amino acid derivative for peptide synthesis, featuring a stable tert-butoxycarbonyl group that enables efficient coupling under standard conditions. The pyroglutamine scaffold provides structural rigidity and enhances solubility in organic solvents, facilitating handling and integration into complex sequences.

Application

Boc-L-Pyroglutaminol serves as a stable, bench-ready building block for the synthesis of pyrrolidine-containing peptides and heterocyclic scaffolds. Its N-Boc protection ensures compatibility with standard amine coupling protocols, while the hydroxyl group enables selective derivatization or incorporation into cyclic structures. Functions effectively in solid-phase and solution-phase peptide synthesis workflows.

General Information

CAS No. 81658-25-5
Cat. No. CS-W022605
Purity ≥95%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₇NO₄
Molecular Weight 215.25
Synonym(s) tert-Butyl (2S)-2-(hydroxymethyl)-5-oxopyrrolidine-1-carboxylate
SMILES O=C1CC[C@@H](CO)N1C(OC(C)(C)C)=O

Computational Chemistry Data

TPSA 66.84
LogP 0.9048
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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Boc-L-Pyroglutaminol

CAS No. 81658-25-5

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