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CS-W001157 4
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2-Butyl-4-chloro-5-formylimidazole Losartan Impurity

  • CAS No. 83857-96-9

  • Cat. No. CS-0229153
  • Molecule weight186.64
  • Purity≥98%
  • MDL No.MFCD01934396

*For research and further manufacturing use only, not for direct human use.

2-Butyl-4-chloro-5-formylimidazole Losartan Impurity|CS-0229153

Structure of 83857-96-9

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General Information

  • CAS No. 83857-96-9
  • Cat. No. CS-0229153
  • Purity ≥98%
  • MDL No. MFCD01934396
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁ClN₂O
  • Molecular Weight 186.64
  • Synonym(s) 2-Butyl-5-Chloroimidazole-4-Carboxaldehyde
  • SMILES C(C1=NC(=C(Cl)[NH]1)C=O)CCC

Synthesis

  • Route1
    • null|null
      57246-71-6
    • null|null
      68-12-2
    • Glycine, 99%|CS-1269057
      56-40-6
    • ~70%
    • 2-Butyl-4-chloro-5-formylimidazole Losartan Impurity|CS-0229153
      83857-96-9

    References

    • DISHMAN PHARMACEUTICALS AND CHEMICALS LTD; Henk Plum Patent: US2008/200690 A1, 2008 ; Location in patent: Page/Page column 4-5 ;
  • Route2
    • (2-Butyl-4-chloro-1H-imidazol-5-yl)methanol Losartan Impurity|CS-0229759
      79047-41-9
    • ~78%
    • 2-Butyl-4-chloro-5-formylimidazole Losartan Impurity|CS-0229153
      83857-96-9

    References

    • Carini, David J.; Duncia, John V.; Aldrich, Paul E.; Chiu, Andrew T.; Johnson, Alexander L.; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 8 p. 2525 - 2547
  • Route3
    • Imidazole Ondansetron Impurity|CS-0229601
      288-32-4
    • (2-Butyl-4-chloro-1H-imidazol-5-yl)methanol Losartan Impurity|CS-0229759
      79047-41-9
    • ~%
    • 2-Butyl-4-chloro-5-formylimidazole Losartan Impurity|CS-0229153
      83857-96-9

    References

    • US5128355 A1, ; US 5128355 A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H317-H401-H411
Precautionary Statements : P261-P272-P273-P280-P302+P352-P363-P391-P501

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   2.2182
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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