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Structure of 850142-73-3
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6-Bromo-2-fluoro-3-methoxypyridine features a trifunctional pyridine core with bromo, fluoro, and methoxy groups positioned for orthogonal reactivity. This electron-deficient heterocycle enables selective cross-coupling and C–H functionalization under mild conditions, delivering access to complex pharmaceutical intermediates with high regiocontrol.
6-Bromo-2-fluoro-3-methoxypyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the fluorine and methoxy substituents provide tunable electronic effects and enhanced metabolic stability. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: