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Structure of 864373-47-7
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Oxetane-2-carboxylic acid is a strained, four-membered cyclic ether bearing a carboxylic acid group at the 2-position. This structure imparts high reactivity in bioorthogonal conjugations and enables direct incorporation into peptide backbones. The oxetane ring facilitates rapid cyclization under physiological conditions while maintaining stability during storage and handling.
Oxetane-2-carboxylic acid serves as a valuable building block in medicinal chemistry, enabling the incorporation of a strained, bioisostatic oxetane ring into drug candidates. Its carboxylic acid functionality facilitates direct coupling reactions and derivatization under standard conditions. The molecule exhibits good bench stability and compatibility with diverse functional groups, making it suitable for modular synthesis of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: