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Structure of 870718-07-3
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3-Benzyloxy-2,6-difluorophenylboronic acid features a strategically positioned benzyloxy group and two fluorine atoms that enhance electronic effects and metabolic stability. This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering functionalized aryl scaffolds with high efficiency and excellent tolerance to diverse reaction environments.
3-Benzyloxy-2,6-difluorophenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The ortho-fluoro substituents enhance reactivity through stabilizing electronic effects and facilitate directed metalation, while the benzyloxy group provides orthogonal protection for phenolic functionalities. Its bench-stable nature and compatibility with diverse reaction partners make it well-suited for iterative synthesis of complex aryl architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: