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Structure of 886779-69-7
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tert-Butyl 3-(trifluoromethyl)piperazine-1-carboxylate features a trifluoromethyl-substituted piperazine core with a robust tert-butoxycarbonyl protecting group. This stable, moisture-tolerant reagent integrates readily into medicinal chemistry workflows, enabling efficient access to bioactive trifluoromethylated piperazines through mild deprotection.
tert-Butyl 3-(trifluoromethyl)piperazine-1-carboxylate serves as a stable, bench-ready building block for the synthesis of trifluoromethylated piperazine derivatives. Its tert-butyl carbamate group enables straightforward deprotection under mild acidic conditions, while the trifluoromethyl substituent imparts enhanced metabolic stability and lipophilicity. The molecule functions effectively in coupling reactions, facilitates access to bioactive scaffolds in medicinal chemistry, and exhibits excellent functional group tolerance in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: