Ethyl 2-(2,4,6-trichloropyrimidin-5-yl)acetate

CAS No. 889944-72-3
Cat. No. CS-W006485
Molecule weight269.51
Purity≥98%
MDL No.MFCD07776806

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-(2,4,6-trichloropyrimidin-5-yl)acetate|CS-W006485

Structure of 889944-72-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 889944-72-3
Cat. No. CS-W006485
Purity ≥98%
MDL No. MFCD07776806
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇Cl₃N₂O₂
Molecular Weight 269.51
Synonym(s) Ethyl 2-(2,4,6-Trichloro-5-pyrimidinyl)acetate
SMILES O=C(OCC)CC1=C(Cl)N=C(Cl)N=C1Cl

Description

Ethyl 2-(2,4,6-trichloropyrimidin-5-yl)acetate features a trichloropyrimidine core paired with an acetyl ester side chain, enabling direct incorporation into heterocyclic synthesis. The electron-deficient pyrimidine ring facilitates nucleophilic substitution, while the ethyl ester group supports subsequent derivatization under standard conditions. This compound serves as a key building block for pharmaceutical intermediates and agrochemicals requiring halogenated heterocycles.

Application

Ethyl 2-(2,4,6-trichloropyrimidin-5-yl)acetate serves as a versatile building block for the synthesis of pyrimidine-based heterocycles, enabling efficient access to medicinally relevant scaffolds. The trichloropyrimidine core exhibits high electrophilicity, facilitating nucleophilic substitution with amines, thiols, and alcohols under mild conditions. Its ethyl ester functionality supports further derivatization via hydrolysis or reduction. Bench-stable and readily purified by column chromatography, it functions reliably in multi-step syntheses requiring functional group tolerance and predictable reactivity.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 52.08
LogP 2.5424
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 3

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

889944-72-3 sigma889944-72-3 manufacturer889944-72-3 price889944-72-3 structure889944-72-3 SDSbuy 889944-72-3889944-72-3 supplier889944-72-3 uses889944-72-3 molecular weightprice of 889944-72-3889944-72-3 chemical name formula of 889944-72-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Ethyl 2-(2,4,6-trichloropyrimidin-5-yl)acetate

CAS No. 889944-72-3

Recommended Products