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Structure of 89197-62-6
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5-Fluorobenzofuran-2-carboxylic acid integrates a fluorinated benzofuran scaffold with a carboxylic acid handle, enabling direct functionalization in synthetic routes. The electron-deficient aromatic system enhances reactivity in coupling processes, while the bench-stable functionality supports efficient derivatization under standard conditions.
5-Fluorobenzofuran-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds via standard amide coupling and Suzuki-Miyaura cross-coupling reactions. The fluorinated benzofuran core provides enhanced metabolic stability and modulates electronic properties, while the carboxylic acid functionality facilitates straightforward derivatization and purification. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: