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CS-W001157 4
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1-(2-(4-Nitrophenoxy)ethyl)piperidine

  • CAS No. 92033-76-6

  • Cat. No. CS-0212063
  • Molecule weight250.29
  • Purity≥98%
  • MDL No.MFCD01308502

*For research and further manufacturing use only, not for direct human use.

1-(2-(4-Nitrophenoxy)ethyl)piperidine|CS-0212063

Structure of 92033-76-6

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General Information

  • CAS No. 92033-76-6
  • Cat. No. CS-0212063
  • Purity ≥98%
  • MDL No. MFCD01308502
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈N₂O₃
  • Molecular Weight 250.29
  • Synonym(s) 1-[2-(4-nitrophenoxy)ethyl]piperidine
  • SMILES C1CCN(CC1)CCOC2=CC=C(C=C2)[N+](=O)[O-]

Synthesis

  • Route1

    References

    • Butler, Christopher R.; Edwards, James P.; Fourie, Anne M.; Grice, Cheryl A.; Karlsson, Lars; Savall, Brad M.; Tays, Kevin L.; Wei, Jianmei Patent: US2006/223792 A1, 2006 ; Location in patent: Page/Page column 27 ; US 20060223792 A1
  • Route2
    • null|null
      100-02-7
    • 2-Piperidinoethyl chloride hydrochloride Raloxifene  Impurity|CS-0229092
      2008-75-5
    • ~73%
    • 1-(2-(4-Nitrophenoxy)ethyl)piperidine|CS-0212063
      92033-76-6

    References

    • Kuethe, Jeffrey T.; Wong, Audrey; Davies, Ian W. Organic Letters, 2003 , vol. 5, # 21 p. 3975 - 3978
  • Route3

    References

    • AMGEN INC. Patent: WO2005/42518 A2, 2005 ; Location in patent: Page/Page column 100 ;

Safety Information

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Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   55.61
  • LogP   2.4595
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   5

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