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Structure of 947275-74-3
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tert-Butyl (R)-2-(2-hydroxyethyl)piperazine-1-carboxylate features a chiral piperazine core with a pendant hydroxyl-bearing ethyl chain, enabling selective conjugation and derivatization in asymmetric synthesis. The tert-butyl ester group provides stability and convenient deprotection under mild acidic conditions, facilitating integration into complex molecular architectures. This scaffold serves as a versatile intermediate for bioactive compound development.
tert-Butyl (R)-2-(2-hydroxyethyl)piperazine-1-carboxylate serves as a chiral piperazine building block for medicinal chemistry, enabling efficient access to bioactive scaffolds. The protected piperazine core exhibits excellent functional group tolerance and bench stability, facilitating coupling reactions with carboxylic acids, sulfonyl chlorides, and electrophiles. The pendant hydroxyl group provides a handle for further derivatization, including etherification or oxidation to aldehyde, supporting modular synthesis of complex heterocyclic systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: