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Structure of 957770-66-0
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N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(8α,9S)-6'-methoxycinchonan-9-yl]urea features a sterically defined cinchona alkaloid scaffold paired with a highly electron-deficient aryl urea. This combination enables strong chiral recognition in asymmetric catalysis, delivering high enantioselectivity in phase-transfer and organocatalytic transformations under ambient conditions.
N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(8α,9S)-6'-methoxycinchonan-9-yl]urea serves as a chiral, sterically defined urea scaffold enabling asymmetric catalysis in enantioselective transformations. The trifluoromethylated aryl group enhances electron deficiency and metabolic stability, while the cinchona-derived moiety provides a rigid, functionalized chiral environment. This structure facilitates hydrogen-bonding interactions in organocatalytic processes, particularly in phase-transfer and Michael additions, with demonstrated utility in modular synthesis of bioactive heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: