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CS-W001157 4
Total: USD 88.00

3-(3-Methylphenyl)propionic acid

  • CAS No. 3751-48-2

  • Cat. No. CS-M2097
  • Molecule weight164.20
  • Purity≥95%
  • MDL No.MFCD00060326

*For research and further manufacturing use only, not for direct human use.

3-(3-Methylphenyl)propionic acid|CS-M2097

Structure of 3751-48-2

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General Information

  • CAS No. 3751-48-2
  • Cat. No. CS-M2097
  • Purity ≥95%
  • MDL No. MFCD00060326
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₂
  • Molecular Weight 164.20
  • Synonym(s) 3-(3-Methylphenyl)propanoic acid; m-Methylhydrocinnamic acid
  • SMILES OC(CCC1=CC(C)=CC=C1)=O

Description

3-(3-Methylphenyl)propionic acid features a benzylic propionic acid chain attached to a meta-methyl-substituted phenyl ring, delivering enhanced lipophilicity and metabolic stability. This structural motif enables integration into bioactive molecules requiring aromatic hydrophobicity and controlled release profiles.

Application

3-(3-Methylphenyl)propionic acid serves as a valuable building block for pharmaceutical and agrochemical synthesis, enabling the construction of biologically relevant aromatic-aliphatic scaffolds. Its well-defined structure supports reliable functionalization at both the carboxylic acid and aromatic ring sites, facilitating coupling reactions, derivatization, and incorporation into complex molecular architectures with predictable reactivity and bench stability.

Synthesis

  • Route1
    • null|null
      313058-61-6
    • ~98%
    • In-stock
      3-(3-Methylphenyl)propionic acid|CS-M2097
      3751-48-2

    References

    • Orita, Akihiro; Yaruva, Jayamma; Otera, Junzo Angewandte Chemie - International Edition, 1999 , vol. 38, # 15 p. 2267 - 2270
  • Route2

    References

    • Journal of the Chemical Society, , p. 357,362
  • Route3
    • 2-(3-Methylbenzyl)malonic acid|CS-0660846
      251963-45-8
    • ~90%
    • In-stock
      3-(3-Methylphenyl)propionic acid|CS-M2097
      3751-48-2

    References

    • Wigchert, Suzanne C. M.; Zwanenburg, Binne Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 18 p. 2617 - 2623

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.01222
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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